PopLife workflow

PopLife provides a standardized workflow for transforming population genomic data into interactive genome browser tracks. The pipeline supports three entry points: whole-genome sequencing (WGS) reads, RAD-seq reads, or pre-computed VCF files, and generates a comprehensive collection of population genomics statistics that can be explored through the PopLife Browser.

The workflow integrates widely used bioinformatics software, including FastQC, fastp, bwa-mem, ANGSD, GATK, PLINK, selscan and JBrowse2, within a unified and reproducible analysis pipeline.

Overview of the PopLife analysis workflow

Figure. Overview of the PopLife analysis workflow, from raw sequencing data to interactive population genomics browsing.